COVID-19 is not only the most savage health crisis in a century, but it also poses a devastating threat to the global economy. Two years after the outbreak, there is still no consensus about the optimal solution to the pandemic. Nevertheless, some societies in Asia and Oceania have apparently performed better than other places in controlling the disease. Recently, as mass vaccination has been accomplished in several countries, “co-existence” rather than “zero-tolerance” has been adopted as an exit strategy. On 15 January 2022, Prof. CHEUNG, Prof. FUNG, and Prof. WU offered policy suggestions, comparing the performances of anti-COVID strategies between Hong Kong and the rest of the world.